Flumethasone (Flucort) 0.5mg/ml 100ml

Description

FLUMETHASONE INJECTION is a chemical modification of prednisolone, which possesses greater anti-inflammatory and gluconeogenic properties than the parent compound when compared on an equivalent basis. Due to the potency of FLUMETHASONE INJECTION, dosage recommendations should be consulted prior to drug administration.  The structural formula is as follows: Active ingredient:  Flumethasone 0.5mg/ml  Preservative:  benzyl alcohol 9mg/ml Description:  The active ingredient of FLUMETHASONE INJECTION is flumethasone which occurs as a white to creamy white, odorless, crystalline powder.  The appearance of FLUMETHASONE INJECTION injection is a clear, colorless to slightly yellowish, mobile liquid. Experimental Studies:  The acetate of flumethasone has been reported to have approximately 700 times the activity of hydrocortisone in the rat liver glycogen disposition assay 1,2. Veterinary experimental studies utilizing eosinophil depression in normal dogs and blood glucose levels and eosinophil depression in normal cattle as parameters of drug activity in comparison tests involving dexamethasone  and prednisone, suggest gluconeogenic  and anti-inflammatory potencies for flumethasone of the following approximate order:  Four times that of dexamethasone.  Sixty to eighty times that of prednisone. Clinical evidence of drug potency obtained during evaluation of the compound further substantiates the above experimental findings. FLUMETHASONE INJECTION is recommended for various rheumatic, allergic, dermatologic and other disease states which are known to be responsive to the anti-inflammatory corticoids. Bovine Indications: 1.  Ketosis. 2.  Musculoskeletal conditions, due to the inflammation of muscles or joints and accessory structures where permanent structural changes do not exist such as arthritis, sprains, myositis or muscular soreness. 3.  Supportive therapy in milk fever, acute mastitis, shipping fever, metritis, pneumonia and founder. Equine Indications: